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Fig. 5 | Molecular Medicine

Fig. 5

From: Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms

Fig. 5

Representative histological aortic sections derived from untreated and AngII infused mice. a Samples were stained with hematoxylin/eosin (HE) for morphological analysis and with Sirius Red for detection of collagens. b Immunohistochemical analysis of leukocyte infiltration (CD45) and proliferating cells (Ki67); n = 3 for WT - Ang II; n = 6 for Aim2−/− − AngII; n = 4 for WT + Ang II; n = 6 for Aim2−/− + AngII. c Quantitative analysis of proliferating cells (Ki67 positive) within the media of abdominal aortic regions. Proliferating (Ki67 positive) cells were counted in abdominal aortic sections of both, dilated and undilated samples. Shown is the mean and SD of WT control (n = 7), Aim2−/− control (n = 6), WT + AngII (n = 4), and Aim2−/− + AngII (n = 11) samples. Data were analyzed. by one-way ANOVA. ns: not significant, ****: P < 0.0001

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Molecular Medicine

ISSN: 1528-3658