Fig. 1
From: The role of host defences in Covid 19 and treatments thereof
Canonical and alternative transsulfuration pathways. The canonical pathway, i.e. transulfuration of homocysteine to cysteine and then GSH synthesis, are shown by black lines; alternative pathways, leading to H2S release, are shown by red lines. The products of H2S releasing reactions, functioning as surrogate markers of H2S release are shown in green colour: Lanthionine reports on H2S from CBS reactions; Homolanthionine reports on H2S from CSE reactions; Pyruvate reports on intramitochondrial release by 3MST; Sulphates (SO42-) reports on H2S oxidation on the respiratory chain