Fig. 4

M3 improves cardiac function in neonatal sepsis. 16 h after cecal slurry injection, echocardiogram was performed on mouse pups. a Representative still images of B and M-mode echocardiogram findings. The B mode is the top portion of the images, while the M mode is the wave pattern, which is shown at the bottom portion of the images. b CO was reduced by sepsis induction while M3 treatment was able to ameliorate some sepsis-induced dysfunction. c Left-ventricular end diastolic diameter was reduced in vehicle-treated septic pups as compared to M3-treated pups. Data are expressed as means ± SE (sham = 9, vehicle = 6, and M3 = 7 pups). Multiple groups were compared by one-way ANOVA and Tukey method (*p < 0.05 vs. sham; ^#p < 0.05 vs. Vehicle)