Fig. 5
From: D-allose alleviates ischemia/reperfusion (I/R) injury in skin flap via MKP-1
D-allose inhibited the deactivation of ERK1/2 signal pathway and the expressions of genes related to programmed necrosis in skin flap injured by I/R. a Protein blots and relative protein expressions of RIP1, RIP3, MLKL, PGAM5 and Drp1 were determined by Western blot in Control, IR, D-allose and PD groups; b Protein blots and relative protein expressions of MKP-1, p-ERK1/2 and ERK1/2 were determined by Western blot in each group. Bars indicated means ±SD. ***P < 0.001, **P < 0.01 vs. Control; ###P < 0.001, ##P < 0.01 vs. IR; ^^^P < 0.001, ^^P < 0.01 vs. D-allose