Fig. 4
From: Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway
Aspirin induces autophagy in CRC cells a mCherry-GFP-LC3 detects changes in autophagic flow in CRC cells treated with aspirin. b qRT-PCR was used to detect changes of MAP1LC3 (LC3) and BECN1 in CRC cells after aspirin treatment. (n = 3) Mean ± SD. *P < 0.05, **P < 0.01 and ***P < 0.001 (vs. normal group). c The results of MAP1LC3 (LC3) protein expression in differently treated groups in HCT-116 cells. d The results of MAP1LC3 (LC3) protein expression in differently treated groups in RKO cells. e The results of BECN1 protein expression in differently treated groups in HCT-116 cells. f The results of BECN1 protein expression in differently treated groups in RKO cells. All experiments were repeated 3 times, (n = 3) Mean ± SD. *P < 0.05, **P < 0.01 and ***P < 0.001 (vs. normal group)