Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: Long non-coding RNA CIR inhibits chondrogenic differentiation of mesenchymal stem cells by epigenetically suppressing ATOH8 via methyltransferase EZH2

Fig. 5

LncRNA CIR binds to EZH2 and silences ATOH8 expression. a Western blot analysis of EZH2, ATOH8 and H3K27me3 in transfected cells. b ChIP analysis was performed to analyze the interactions of EZH2 and H3K27me3 with ATOH8 promoter in transfected cells. c qRT-PCR analysis of lncRNA CIR level in transfected cells. d Western blot analysis of protein levels of ATOH8, H3K27me3 in transfected cells. n = 3; *P < 0.05; **P < 0.01; ***P < 0.001

Back to article page

Molecular Medicine

ISSN: 1528-3658