Fig. 2

Low responder to the hepatitis B vaccine presented lower frequencies of cTfh cells than controls. a Representative dot plots of gating strategy. b Comparison frequencies of CXCR5+CD4+T cell, CXCR5−CD4+T cell between LR and HR at D7, D14 and D28 and kinetics of Tfh cell in LR and HR from D7 to D28. Median and range bars represent mean ± SEMs
LR low responders, HR hyper responders, D7 range 7–8 days after vaccination, D14 range 14–15 days after vaccination, D28 range 28–29 days after vaccination