Fig. 3

LRRC4 deletion up-regulates NF-κB in EAE mice. a Real-time PCR analysis of cytokine mRNA levels of spinal cords in WT and LRRC4^−/− mice that are healthy or with different clinical scores. b Western blotting analysis and quantification of the western blotting images of spinal cord lysates from WT and LRRC4^−/− mice. Each lane represents samples from an individual mouse. c Western blotting analysis and quantification of the western blotting images of spinal cord lysates in WT and LRRC4^−/− mice that are healthy or with different clinical scores. Results are shown as means ± SEM (n = 3). *p < 0.05, **p < 0.01