Fig. 2
From: MiR-206 regulates the Th17/Treg ratio during osteoarthritis
MiR-206 promoted the generation of Th17 cells via targeting SOCS3. A Expression levels of SOCS3 in CD4+T cells in response to miR-206 overexpression or knockdown; B Schematic illustration of miR-206 binding sites in SOCS3; C Luciferase assays of the indicated cells transfected with pmirGLO-SOCS3-WT/MUT reporters and miR-206 mimic/mimic NC; D, E The percentage of Th17 cells in CD4+ T cells in response to co-overexpression or co-knockdown of miR-206 and SOCS3. All experiments were repeated three times. Data are expressed as mean ± SD. **P < 0.01; ##P < 0.01