Fig. 2

CircMTO1 inhibited the proliferation and migration and induced the apoptosis of ox-LDL-stimulated VSMCs. A The mRNA expression levels of circMTO1 and MTO1 in VSMCs transfected with pcDNA 3.1-circMTO1. B, C The effect of circMTO1 overexpression on cell viability and proliferation determined by CCK8 and BrdU incorporation assays. D The effect of circMTO1 overexpression on apoptosis. E The effect of circMTO1 on cell migration. **P < 0.01, #P < 0.05 compared with NC + ox-LDL + capecitabine. Ca. indicates the capecitabine