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Fig. 3 | Molecular Medicine

Fig. 3

From: CircMTO1 inhibits ox-LDL-stimulated vascular smooth muscle cell proliferation and migration via regulating the miR-182-5p/RASA1 axis

Fig. 3

CircMTO1 acted as a sponge for miR-182-5p in AS. A Starbase predicted putative targeting sites for circMTO1 and miR-182-5p. B Luciferase activity in VSMCs co-transfected with miR-182-5p mimic and pmirg10-circMTO1-WT or pmirg10-circMTO1-Mut vector. C Effect of si-circMTO1 or circMTO1 overexpression plasmid on miR-182-5p expression in VSMCs. D Levels of miR-182-5p expression in serum of AS patients (n = 55) and healthy volunteers (n = 55). E Correlation of circMTO1 and miR-182-5p in serum of AS patients by Pearson analysis (n = 66). **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658