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Fig. 7 | Molecular Medicine

Fig. 7

From: The long non-coding RNA DKFZp434J0226 regulates the alternative splicing process through phosphorylation of SF3B6 in PDAC

Fig. 7

SF3B6 is required in DKFZp434J0226 (DKFZ)-induced proliferation and migration. A–C Cell growth curves assay (A), soft agar colony formation assay (B), and western blotting of PCNA (C) demonstrating that SF3B6 knockdown rescues DKFZ-induced cell proliferation. D Migration assay demonstrating that SF3B6 knockdown rescues DKFZ-induced cell migration. E RT-qPCR demonstrating that SF3B6 knockdown rescues DKFZ-induced alternative splicing of MDM-4. A Data are shown as mean ± SD; *P < 0.05 vs. Mock and N; **P < 0.01 vs. DKFZ. B–E Data are shown as mean ± SD; *P < 0.05, **P < 0.01. Scale bars refer to 100 μm

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Molecular Medicine

ISSN: 1528-3658