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Fig. 3 | Molecular Medicine

Fig. 3

From: CB2-mediated attenuation of nucleus pulposus degeneration via the amelioration of inflammation and oxidative stress in vivo and in vitro

Fig. 3

CB2 activation attenuates the degeneration of NPCs. A, B CCK-8 results showing that both JWH133 and AM630 have no toxicity in NPCs at concentrations under 10 µM C RT-qPCR results for collagen II, aggrecan, MMP3 and MMP13 (*p < 0.05). D Representative image of ICC staining for collagen II, aggrecan, MMP3 and MMP13 in NPCs; scale bar, 100 μm. E Western blot results for collagen II, aggrecan, MMP3 and MMP13. (n = 3 Independent experiments)

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