Fig. 3From: CB2-mediated attenuation of nucleus pulposus degeneration via the amelioration of inflammation and oxidative stress in vivo and in vitroCB2 activation attenuates the degeneration of NPCs. A, B CCK-8 results showing that both JWH133 and AM630 have no toxicity in NPCs at concentrations under 10 µM C RT-qPCR results for collagen II, aggrecan, MMP3 and MMP13 (*p < 0.05). D Representative image of ICC staining for collagen II, aggrecan, MMP3 and MMP13 in NPCs; scale bar, 100 μm. E Western blot results for collagen II, aggrecan, MMP3 and MMP13. (n = 3 Independent experiments)Back to article page