Fig. 4

GPER inhibits mechanical stress-mediated actin polymerization and Piezo1 activation. a Immunofluorescence staining F-actin and Piezo1 (n = 3). b Cell viabilities for chondrocytes treated with mechanical stress, 10 μM G-1, and 8 μM cytoD (n = 3). c Protein expression of Bax and Bcl-2 for chondrocytes treated with mechanical stress, 10 μM G-1, and 8 μM cytoD (n = 3). All data are presented in mean ± SD