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Fig. 4 | Molecular Medicine

Fig. 4

From: Reversible dysregulation of renal circadian rhythm in lupus nephritis

Fig. 4

Dysregulated circadian regulation of renal salt excretion and blood pressure in nephritic mice A Urine Na + /Creatinine ratio; B Urine K + /Creatinine ratio Urine pH; C Serum aldosterone; D Urine pH; E, F: systolic (black) and diastolic (grey) blood pressure in young (E) and nephritic (F) mice shows reverse dipping pattern in nephritic mice;—each symbol represents one mouse. G Heatmap of genes that contribute to regulation of blood pressure. Samples are the same as those shown in Additional file 1: Figure S2. Rhythmicity was evaluated by Cosinor analysis (Ac = acrophase)

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