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Fig. 6 | Molecular Medicine

Fig. 6

From: Suppression of CRLF1 promotes the chondrogenic differentiation of bone marrow-derived mesenchymal stem and protects cartilage tissue from damage in osteoarthritis via activation of miR-320

Fig. 6

knockdown of CRLF1 or over-expression of miR-320 can inhibit the apoptosis of primary chondrocytes isolated from the articular cartilage tissues of OA mice. A The CRLF1 expression in chondrocytes transfected with shCRLF1, miR-320 mimics and their controls. B Apoptosis was examined by flow cytometric analysis using Annexin V/PI assay. C The expression of apoptosis-related proteins in different transfected groups. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001

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Molecular Medicine

ISSN: 1528-3658