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Fig. 4 | Molecular Medicine

Fig. 4

From: A higher bacterial inward BCAA transport driven by Faecalibacterium prausnitzii is associated with lower serum levels of BCAA in early adolescents

Fig. 4

Associations of metagenomic species with serum BCAA, metabolic traits and fecal SCFA. A, B multiple linear regression models for the association between the arcsin-sqrt normalized abundance of Faecalibacterium and Roseburia species and serum BCAA levels adjusting for age, sex and body fat percentage. B heat map of the partial Spearman’s rank correlation coefficient between species relative abundance and metabolic traits. C Heat map of the partial Spearman’s rank correlation coefficient of fecal SCFA concentrations with species abundance and metabolic traits. A, B regression models were adjusted for age, sex and body fat percentage, gray shading represents 95% CI. C, D partial correlations for anthropometric traits were adjusted for age and sex, and for biochemical variables were further adjusted for body adiposity. E heat map of the partial Spearman’s rank correlation coefficient between selected species and total serum BCAA levels. P-values were calculated using partial correlations adjusted for Model 1: age and sex. Model 2: Model 1 + body fat percentage. *P < 0.05. BCAA branched-chain amino acids, SCFA short-chain fatty acids

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Molecular Medicine

ISSN: 1528-3658