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Table 3 Distribution of the basic characteristics of CRC patients and controls

From: Inhibitory immune checkpoints PDCD-1 and LAG-3 hypermethylation may reduce the risk of colorectal cancer

Variables

CRCs (n = 361), n%

Controls (n = 358), n%

*P value

Age (years)

  

 < 0.0001

Mean ± SD

60.38 ± 10.28

55.82 ± 11.92

< 0.0001

  ≤ 50

53 (14.68%)

104 (29.05%)

 

 50-

114 (31.58%)

102 (28.49%)

 

 60-

135 (37.40%)

116 (32.40%)

 

  > 70

59 (16.34%)

36 (10.06%)

 

Gender

  

0.111

 Male

225 (62.33%)

202 (56.42%)

 

 Female

136 (37.67%)

156 (43.58%)

 

BMI

  

0.146

Mean ± SD

23.37 ± 4.36

23.81 ± 3.84

 

  < 18.5

20 (5.54%)

16 (4.47%)

 

 18.5-

107 (29.64%)

104 (29.05%)

 

  ≥ 23

234 (64.82%)

238 (66.48%)

 

Education

  

0.080

 Primary school and below

161 (44.60%)

134 (37.43%)

 

 Junior senior and above

200 (55.40%)

224 (62.57%)

 

Ethic group

  

0.847

 Han

349 (96.68%)

344 (96.09%)

 

 Others

12 (3.32%)

14 (3.91%)

 

Marriage status

  

0.896

 Married

331 (90.94%)

325 (90.78%)

 

 Others

30 (9.06%)

33 (9.22%)

 

Occupation

  

0.507

 White collar

256 (70.91%)

262 (73.18%)

 

 Blue collar

105 (29.09%)

96 (26.82%)

 

Family history of CRC

  

0.138

 No

318 (88.09%)

328 (91.62%)

 

 Yes

43 (11.91%)

30 (8.38%)

 

Alcohol drinking

  

< 0.0001

 No

204 (56.51%)

252 (70.39%)

 

 Yes

157 (43.49%)

106 (29.61%)

 

Smoking

  

0.668

 No

253 (70.08%)

269 (75.14%)

 

 Yes

108 (29.92%)

89 (24.86%)

 
  1. *P values < 0.05 were considered statistically significant and were indicated in bold
  2. CRC, colorectal cancer; SD, standard deviation; BMI, body mass index