Fig. 3
From: Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway
Hsp90 correlated with PD-L1 and HER2 expression in HPV16+ cervical cancer. A PD-L1 and HER2 gene expression in normal and cancer tissues. B correlation analysis among Hsp90, PD-L1 and HER2 expression in normal and cancer tissues. C PD-L1 and HER2 gene expression in normal (H8) and cancer (Caski and SiHa) cervical epithelial cell lines. D Western blot of PD-L1 and HER2 expression in normal (H8) and cancer (Caski and SiHa) cervical epithelial cell lines. Clinical samples: N = 25 in normal tissue group, N = 38 of cancer tissue group. *p < 0.05. Cell culture study: N = 3 in each group. *p < 0.05 or **p < 0.01