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Fig. 4 | Molecular Medicine

Fig. 4

From: Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway

Fig. 4

HER2 increased PD-L1 expression via PI3K/AKT to promote the proliferation and migration of cervical cancer cells. A Western blotting image and analysis of HER2, AKT, p-AKT. PD-L1 and tubulin expressions in control, sh-NC, sh-HER2#1, sh-HER2#2, sh-HER2#1+SC79, and sh-HER2#2+SC79 treated Caski and SiHa cells. B MTT assay evaluating cell proliferation. C Transwell assay evaluating cell migration. N = 3 in each group. *p < 0.05, **p < 0.01 or ***p < 0.001

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