Fig. 6
From: Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway
Knockdown Hsp90 inhibited xenograft tumor growth using SiHa cells. A gross photos of excised tumors in control, sh-NC, sh-Hsp90, sh-Hsp90+vector and sh-Hsp90+PD-L1 groups. B tumor weight and C tumor volume. D IHC staining by Ki-67 to analyze cell proliferation. E H&E staining was used to test lung metastatic nodules. F Western blotting image of Hsp90, HER2, p-HER2, AKT, p-AKT. PD-L1 and tubulin expressions. N = 6 in each group, *p < 0.05, **p < 0.01 or ***p < 0.001