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Fig. 2 | Molecular Medicine

Fig. 2

From: Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway

Fig. 2

Inhibition of PI3K/AKT pathway suppressed the function of TRIM14 in AML. A–B The expression of TRIM14, cleaved caspase-3, AKT and p-AKT in AML cells after transfecting with TRIM14 siRNAs (A) or overexpressed plasmid (B). C The proliferation of HL-60 with the application of oeTRIM14 and LY294002. D The expression of AKT and p-AKT in HL-60 cells with the application of oeTRIM14 and LY294002. * p < 0.05 vs oeNC + DMSO, *** p < 0.001 vs oeNC + DMSO; !!*p < 0.05 vs oeTRIM14 + DMSO; !!!***p < 0.001 vs oeTRIM14 + DMSO

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Molecular Medicine

ISSN: 1528-3658