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Fig. 1 | Molecular Medicine

Fig. 1

From: Global identification of circular RNAs in imatinib (IM) resistance of chronic myeloid leukemia (CML) by modulating signaling pathways of circ_0080145/miR-203/ABL1 and circ 0051886/miR-637/ABL1

Fig. 1

Among all candidate circRNAs, circ_0080145, circ 0134501, circ 0134491 and circ_0051886 were dysregulated between different CML patient groups, and unlike BCR/ABL1, the level of ABL1 mRNA was higher non-responder patients (*P value < 0.05 vs. responder group). A The relative expression level of circ_0080145 was higher in CML patients sensitive to IM; B The relative expression levels of circ 0051763 were similar in different CML patient groups; C The elative expression level of circ 0134501 was higher in CML patients sensitive to IM; D The relative expression levels of circ 0013745 were similar in different CML patient groups; E The relative expression levels of circ 0076044 were similar in different CML patient groups; F The relative expression levels of circ 0109320 were similar in different CML patient groups; G The relative expression level of circ 0134491 was lower in CML patients sensitive to IM; H The relative expression levels of circ 0049892 were similar in different CML patient groups; I The relative expression levels of circ 0026701 were similar in different CML patient groups; J The relative expression level of circ_0051886 was higher in CML patients sensitive to IM; K The relative expression level of ABL1 mRNA was higher in CML patients sensitive to IM; L The relative expression levels of BCR/ABL1 were similar in different CML patient groups

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