Skip to main content

Table 1 Baseline characteristics of survivor and non-survivor COVID-19 patients at ICU admission

From: Syndecan-1, an indicator of endothelial glycocalyx degradation, predicts outcome of patients admitted to an ICU with COVID-19

 

Total (N = 49)

COVID-19 patients

P

Non-survivors (N = 35)

Survivors (N = 14)

Age, years

65.0 (56.5–72.0) (49)

65.0 (59.0–73.0) (35)

56.5 (53.8–70.8) (14)

0.020

Gender

 Male/female

65.3% (32/49)/34.7% (17/49)

74.3% (26/35)/25.7% (9/35)

42.9% (6/14)/57.1% (8/14)

0.079

Comorbidities/condition

 Smoking

10.2% (5/49)

11.4% (4/35)

7.1% (1/14)

1.000

 Hypertension

49.0% (24/49)

48.6% (17/35)

50.0% (7/14)

0.928

 Diabetes

16.3% (8/49)

11.4% (4/35)

28.6% (4/14)

0.299

 Cardiovascular disease

24.5% (12/49)

25.7% (9/35)

21.4% (3/14)

1.000

 Cerebrovascular disease

14.3% (7/49)

11.4% (4/35)

21.4% (3/14)

0.651

 Chronic lung disease

4.1% (2/49)

5.7% (2/35)

0.0% (0/14)

1.000

 Chronic kidney disease

6.1% (3/49)

2.9% (1/35)

14.3% (2/14)

0.193

 Chronic liver disease

2.0% (1/49)

2.9% (1/35)

0.0% (0/14)

1.000

 Anemia

4.1% (2/49)

0.0% (0/35)

14.3% (2/14)

0.077

 Malignance

4.1% (2/49)

5.7% (2/35)

0.0% (0/14)

1.000

 Autoimmune diseases

2.0% (1/49)

0.0% (0/35)

7.1% (1/14)

0.286

Symptoms and signs

 Fever

85.7% (42/49)

85.7% (30/35)

85.7% (12/14)

1.000

 Fatigue

55.1% (27/49)

57.1% (20/35)

50.0% (7/14)

0.650

 Dyspnea

61.2% (30/49)

68.6% (24/35)

42.9% (6/14)

0.095

 Cough

69.4% (34/49)

68.6% (24/35)

71.4% (10/14)

1.000

 Sputum

55.1% (27/49)

54.3% (19/35)

57.1% (8/14)

0.856

 Pharyngeal pain

14.3% (7/49)

17.1% (6/35)

7.1% (1/14)

0.651

 Abdominal pain

24.5% (12/49)

28.6% (10/35)

14.3% (2/14)

0.495

 Diarrhea

30.6% (15/49)

37.1% (13/35)

14.3% (2/14)

0.220

 Headache

20.4% (10/49)

25.7% (9/35)

7.1% (1/14)

0.287

 Dizziness

8.2% (4/49)

11.4% (4/35)

0.0% (0/14)

0.458

 Nausea

28.6% (14/49)

34.3% (12/35)

14.3% (2/14)

0.294

 Vomiting

24.5% (12/49)

28.6% (10/35)

14.3% (2/14)

0.495

 Anorexia

20.4% (10/49)

25.7% (9/35)

7.1% (1/14)

0.287

 Myalgia

20.4% (10/49)

22.9% (8/35)

14.3% (2/14)

0.779

Disease severity status

 Severe/Critically severe

22.4% (11/49)/77.6% (38/49)

0.0% (0/35)/100.0% (35/35)

78.8% (11/14)/21.4% (3/14)

 < 0.001

Treatment

 MV

66.7% (32/48)

85.3% (29/34)

21.4% (3/14)

 < 0.001

  Invasive MV

90.6% (29/32)

89.7% (26/29)

100% (3/3)

1.000

  PEEP (cm H2O)

12.0 (10.0–14.0) (29)

12.0 (10.0–14.0) (26)

14.0 (NA) (3)

0.948

  PaCO2 (mmHg)

49.0 (42.0–58.8) (28)

49.0 (42.0–58.5) (21)

49.0 (47.0–64.0) (7)

0.876

  Oxygenation index (mmHg)

135.5 (84.2–276.5) (23)

117.9 (79.4–197.1) (19)

311.7 (286.5–356.8) (4)

0.010

  Lactate (mmol/L)

21.0 (7.0–34.0) (16)

23.0 (15.5–34.0) (12)

7.0 (5.0–33.0) (4)

0.350

  1. Bold values indicate statistical significance
  2. Data are presented as median (Q1–Q3) (N) or % (n/N)
  3. COVID-19, coronavirus disease 2019; MV, mechanical ventilation; PEEP, positive end-expiratory pressure; PaCO2, partial pressure of carbon dioxide