Fig. 3From: Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent wayProtein expression level change between control and calcific aortic valves. a Protein expression levels of p-AMPK (Thr172), p-AKT (Ser473), PI3K, p-eNOS (Ser1177), BMP2, and OPN of control (n = 9) and calcific (n = 8) valves were determined by WB and quantification analysis; b protein expression levels of Bax and Bcl2 were determined by WB and quantification analysis. CTL control; CAVD calcific aortic valve disease; *p < 0.05 versus control group (Student’s t-test)Back to article page