From: Long non-coding RNA XIST: a novel oncogene in multiple cancers
Tumor types | Expression | Role | Function role | miRNAs | Related genes | References |
---|---|---|---|---|---|---|
Esophageal cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-101 | EZH2 | Wu et al. 2017a) |
Esophageal cancer | Upregulation | Oncogene | Proliferation, apoptosis, migration, and invasion | miR-494 | CDK6/JAK2/STAT3 | Chen et al. 2019a) |
Esophageal cancer | Upregulation | Oncogene | Cell cycle, proliferation, migration, invasion, and apoptosis | miR-129-5p | CCND1 | Wang et al. 2021) |
Gastric cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-101 | EZH2 | Chen et al. 2016) |
Gastric cancer | Upregulation | Oncogene | Proliferation and invasion | miR-497 | MACC1 | Ma et al. 2017) |
Gastric cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-185 | TGF-β1 | Zhang et al. 2018) |
Gastric cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-337 | JAK2 | Zheng et al. 2020a) |
Gastric cancer | Upregulation | Oncogene | Proliferation, migration, and apoptosis | miR-132 | PXN | Li et al. 2020b) |
Colorectal cancer | Upregulation | Oncogene | Proliferation | miR-132-3p | MAPK1 | Song et al. 2017) |
Colorectal cancer | Upregulation | Oncogene | Proliferation, migration, invasion, emt, and stem cell formation | miR-200b-3p | ZEB1 | Chen et al. 2017) |
Colorectal cancer | Upregulation | Oncogene | Migration and invasion | miR-137 | EZH2 | Liu et al. 2018) |
Colorectal cancer | Upregulation | Oncogene | Proliferation and invasion | miR-34a | WNT1 | Sun et al. 2018b) |
Colorectal cancer | Upregulation | Oncogene | Growth, viability, apoptosis, and emt | miR-486b-5p | NRP-2 | Liu et al. 2019) |
Colorectal cancer | Upregulation | Oncogene | Migration, proliferation, emt, and apoptosis | miR-93-5p | HIF-1A | Yang et al. 2020) |
Colorectal cancer | Upregulation | Oncogene | Proliferation, migration, invasion, and apoptosis | miR-338-3p | PAX5 | Li et al. 2021) |
Colorectal cancer | Upregulation | Oncogene | Proliferation, migration, invasion, and apoptosis | miR-497-5p | FOXK1 | Wang et al. 2020b) |
Colorectal cancer | Upregulation | Oncogene | Chemoresistance | miR-124 | SGK1 | Zhu et al. 2018b) |
Colorectal cancer | Upregulation | Oncogene | Viability, proliferation, apoptosis, and chemoresistance | miR-30a-5p | ROR1 | Zhang et al. 2019c) |
Colorectal cancer | Upregulation | Oncogene | Proliferation, migration, invasion, and chemoresistance | miR-137 | PKM2/PKM1 | Zheng et al. 2020) |
Pancreatic cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-34a-5p | / | Sun et al. 2018a) |
Pancreatic cancer | Upregulation | Oncogene | Proliferation | miR-133a | EGFR | Wei et al. 2017) |
Pancreatic cancer | Upregulation | Oncogene | Proliferation | miR-140/124 | iASPP | Liang et al. 2017) |
Pancreatic cancer | Upregulation | Oncogene | Emt | miR-34a | YAP | Zou et al. 2020) |
Pancreatic cancer | Upregulation | Oncogene | Migration, invasion, and emt | miR-429 | ZEB1 | Shen et al. 2019) |
Pancreatic cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-141-3p | TGF-β2 | Sun and Zhang 2019) |
Pancreatic cancer | Upregulation | Oncogene | Proliferation | miR-137 | Notch1 | Liu et al. 2020) |
Hepatocellular carcinoma | Upregulation | Oncogene | Proliferation | miR-200b-3p | / | Liu and Xu 2019) |
Hepatocellular carcinoma | Upregulation | Oncogene | Proliferation and apoptosis | miR-488 | / | Dong et al. 2020) |
Hepatocellular carcinoma | Upregulation | Oncogene | Proliferation and apoptosis | miR-139-5p | PDK1 | Mo et al. 2017) |
Hepatocellular carcinoma | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-194-5p | MAPK1 | Kong et al. 2018) |