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Fig. 7 | Molecular Medicine

Fig. 7

From: Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway

Fig. 7

Affecting the pathway of PDP1/PDHA1 did not improve the damage caused by CIH exposure. A The study workflow. After 7 days of acclimation, the mice were exposed to the CIH condition for about 3 months, and they were treated with 3-FP at the last 3 weeks. Fear test were conducted as soon as CIH exposure finished. B The structure of 3-FP. C The freezing level of contextual memory among 4 groups. D The freezing level of cued memory among 4 groups. E H&E stained of the hippocampus. Each experiment was repeated three times. Data are shown as the mean ± SEM. Statistical analysis was performed with two-way ANOVA. *p < 0.05 WT group vs WT CIH group. Magnification: 400×. The local details are enlarged in the rectangular frame

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Molecular Medicine

ISSN: 1528-3658