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Fig. 6 | Molecular Medicine

Fig. 6

From: Activation of dopamine receptor D1 promotes osteogenic differentiation and reduces glucocorticoid-induced bone loss by upregulating the ERK1/2 signaling pathway

Fig. 6

Activation of D1R alleviated Dex-induced osteoporosis in vivo. A Representative 3D reconstructions of μCT images and B representative paraffinized sections stained with H&E. C BMD within the region of interest (ROI) was calculated by μCT. D BV/TV E BS/BV, F BS/TV, G Tb. Th, H Tb. N. and I Conn.Dn. J and K BV/TV and BS within the ROI were analyzed by H&E staining. n = 5 per group. NS: Not statistically significant, * p < 0.05, ** p < 0.01, vs. the vehicle group, # p < 0.05, ## p < 0.01, vs. the control group

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