Fig. 5
From: GRK2 regulates group 2 innate lymphoid cell mobilization in sepsis
Reduced IL-33 in aging mice attenuates ILC2p mobilization in sepsis. A Representative flow cytometry plots showing percentages of ILC2p in BM and ILC2 in lung of young and aging mice. Frequency and number of (B) BM ILC2p and C lung ILC2 at 24 h after sham, CLP and CLP + IL-33 (n = 4–5 mice/group). D Percentages of retained ILC2p in BM or ILC2 recruited in lung of mice treated with IL-33 (40 µg/kg B.W.) intravenously 30 min before CLP compared to sham surgery mice. BM ILC2p or lung ILC2 in sham surgery were normalized to 100% (n = 4–5 mice/group). E IL-33 in plasma of aging mice compared to young mice after CLP for up to 24 h (n = 4–5 mice/group). Data shown as mean ± SEM. * P < 0.05, ** P < 0.01