Fig. 4

CREB1 differentially regulated TCEAL2 under normal and cancer stages. A Western blot analysis for TCEAL2 expression was performed with cell lysate from GES-1 and NCI-N87 transfected with CREB1 lentivirus vectors (Left) or siRNA specific to CREB1 (Right). B Correlation between CREB1 and TCEAL2 in diagnostic tumor samples (n = 56, r = 0.062, P = 0.663) and normal samples (n = 52, r = 0.613, P < 0.01). C Representative IHC staining of CREB1 and TCEAL2 in tumor and normal samples (400 ×). *Means significant P-value < 0.05, NS means no significant, correlation between CREB1 and TCAEL2 expression was analyzed by Spearman test