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Fig. 1 | Molecular Medicine

Fig. 1

From: Protective role of trametenolic acid B against sevoflurane-induced cognitive impairments by its different regulatory modalities of mir-329-3p in neurons and microglia

Fig. 1

TAB alleviated the cognitive function of rats exposed to sevoflurane. A The representative trajectories of the rats in the probe trial from the MWM test. B Sevoflurane inhalation led to longer escape latency time, while TAB reduced this time in rats. B TAB administration increased the number of platform crossing, which was reduced by sevoflurane. C The time in target quadrant of rats was shorter in sevoflurane inhalation group than the normal group, but it was promoted by TAB administration. E The freezing time in FCT test was reduced in rats exposed to sevoflurane, and this effect was reversed by TAB treatment. F Time spent in the center of PFT test revealed that sevoflurane and TAB had no significant effects on the behavior of rats. **P < 0.01, ***P < 0.001 compared to normal group; #P < 0.05, ##P < 0.01, ###P < 0.001 compared to SEV group

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Molecular Medicine

ISSN: 1528-3658