Fig. 3
From: EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes
EGF promotes the switch of APCs to iOPCs. A The schematic of EGF and Gefitinib treatments at different time points during Sox10-induced reprogramming. B After infection with Sox10-GFP virus, the cells were cultured in five different culture conditions for 15 days, then immunostaining was performed with O4 antibody. C Quantification of the percentage of O4+ cells in five separate reprogramming cultures. Statistical analyses are presented as Mean ± SD, n = 3. *P < 0.05, **P < 0.01. Scale bars, 50 μm