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Fig. 1 | Molecular Medicine

Fig. 1

From: Glabridin, a bioactive component of licorice, ameliorates diabetic nephropathy by regulating ferroptosis and the VEGF/Akt/ERK pathways

Fig. 1

Bioinformatics analysis of licorice in diabetic nephropathy. A Common targets between putative predicted targets of licorice and targets associated with DN in the GeneCards and DisGeNET databases. B Bioactive component-target network of licorice against DN. The green nodes denote the bioactive components in licorice, and the red nodes denote the corresponding targets of the components. C GO and (D) KEGG enrichment analysis of 40 targets from the network. E Among the 40 targets, the genes in red rectangles were targets of Glab, which were mainly enriched in the VEGF signaling pathway in DN

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