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Fig. 7 | Molecular Medicine

Fig. 7

From: Glabridin, a bioactive component of licorice, ameliorates diabetic nephropathy by regulating ferroptosis and the VEGF/Akt/ERK pathways

Fig. 7

Effects of Glab on the VEGF/Akt/ERK pathway in DN in vitro and in vivo. Western blot was conducted to analyze the protein expression of VEGF, Akt, p-Akt, ERK1/2, and p-ERK1/2 in (A) HG-induced NRK-52E cells and (B) the kidney of DM rats. C Representative images and quantitation of immunohistochemistry for VEGF, p-Akt, and p-ERK1/2 in kidney tissues from rats of diverse groups (***P < 0.005, vs. the control group; #P < 0.05, ##P < 0.01, and ###P < 0.005, vs. the DM group or the HG group)

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Molecular Medicine

ISSN: 1528-3658