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Fig. 3 | Molecular Medicine

Fig. 3

From: α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function

Fig. 3

GTS-21 improves intestinal tight junction (TJ) proteins expressions in DSS-induced colitis. A–D Western blot analysis of mice colonic TJ proteins (ZO-1, claudin-1, occludin, JAM-1) expressions level in different groups. *p < 0.05; **p < 0.01, ***p < 0.001. E–H Representative immunofluorescence of ZO-1 and claudin-1 (red), occludin and JAM-1 (green) in the proximal colon of mice in Ctrl group (DAPI nuclear staining), DSS group, GTS-21 group and α-BGT pretreatment before GTS-21 group. Magnification, ×400. Scale bar, 100 nm

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Molecular Medicine

ISSN: 1528-3658