Fig. 2
From: FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress
FGF1 pretreatment ameliorates LPS-induced oxidative stress via promoting antioxidant defenses. Effects of FGF1 pretreatment on ROS (A), MDA (B), in RAW264.7 cells and mice lung tissues, respectively; scale bar = 64 μm. C, D Immunohistochemistry and WB analysis of SOD2 in lung tissues; scale bar = 64 μm. E, F WB analysis of Nrf2, HO-1 in mice, and cells incubated with varying concentrations of FGF1, respectively. All data were analyzed at 12 h after LPS treatment. Data are presented as mean ± SD (n = 5 per group). *p < 0.05, **p < 0.01; One-way ANOVA with Tukey’s post-hoc test