Fig. 7From: Activation of the sigma-1 receptor exerts cardioprotection in a rodent model of chronic heart failure by stimulation of angiogenesisSchematic representation of the angiogenesis effect of S1R stimulation in the PIHF rats. Stimulation of S1R exerts protective effect in PIHF, which were associated with augmentation of microvascular density in peri-infarct region through activation of the JAK2/STAT3 pathwayBack to article page