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Table 1 Description of participants (N = 156; n = 52 per donor group)

From: Radiation-response in primary fibroblasts of long-term survivors of childhood cancer with and without second primary neoplasms: the KiKme study

 

Donors with at least one second primary neoplasm

Donors with a first primary neoplasm

Cancer-free controls

Female, %

51.92

Median age at sampling [Interquartile Range (IQR)], years

32.00 (28.00–38.20)

32.50 (28.00–38.20)

33.00 (27.80–38.00)

Median age at first neoplasm (IQR), years

8.00 (4.00–11.20)

8.00 (3.75–12.00)

–

Median age at second neoplasm (IQR), years

23.00 (17.00–30.00)

–

–

First neoplasm

 Hodgkin lymphomas

18

18

–

 Lymphoid leukaemias

18

18

–

 Intracranial and intraspinal embryonal tumours

5

5

–

 Non-Hodgkin lymphomas (except Burkitt lymphoma)

4

4

–

 Acute myeloid leukaemias

3

3

–

 Chronic myeloproliferative diseases

1

1

–

 Burkitt lymphoma

1

1

–

 Ependymomas and choroid plexus tumour

1

1

–

 Astrocytomas

1

1

–

Second neoplasm

 Skin carcinomas

25

–

–

 Thyroid carcinomas

17

–

–

 Acute myeloid leukaemias

3

–

–

 Breast Cancer

2

–

–

 Malignant melanomas

2

–

–

 Lymphoid leukaemias

2

–

–

 Ependymomas and choroid plexus tumour

1

–

–

Third neoplasm

 No third neoplasm

49

52

52

 Other specified intracranial and intraspinal neoplasms

2

–

–

 Renal carcinomas

1

–

–