| Donors with at least one second primary neoplasm | Donors with a first primary neoplasm | Cancer-free controls |
---|---|---|---|
Female, % | 51.92 | ||
Median age at sampling [Interquartile Range (IQR)], years | 32.00 (28.00–38.20) | 32.50 (28.00–38.20) | 33.00 (27.80–38.00) |
Median age at first neoplasm (IQR), years | 8.00 (4.00–11.20) | 8.00 (3.75–12.00) | – |
Median age at second neoplasm (IQR), years | 23.00 (17.00–30.00) | – | – |
First neoplasm | |||
 Hodgkin lymphomas | 18 | 18 | – |
 Lymphoid leukaemias | 18 | 18 | – |
 Intracranial and intraspinal embryonal tumours | 5 | 5 | – |
 Non-Hodgkin lymphomas (except Burkitt lymphoma) | 4 | 4 | – |
 Acute myeloid leukaemias | 3 | 3 | – |
 Chronic myeloproliferative diseases | 1 | 1 | – |
 Burkitt lymphoma | 1 | 1 | – |
 Ependymomas and choroid plexus tumour | 1 | 1 | – |
 Astrocytomas | 1 | 1 | – |
Second neoplasm | |||
 Skin carcinomas | 25 | – | – |
 Thyroid carcinomas | 17 | – | – |
 Acute myeloid leukaemias | 3 | – | – |
 Breast Cancer | 2 | – | – |
 Malignant melanomas | 2 | – | – |
 Lymphoid leukaemias | 2 | – | – |
 Ependymomas and choroid plexus tumour | 1 | – | – |
Third neoplasm | |||
 No third neoplasm | 49 | 52 | 52 |
 Other specified intracranial and intraspinal neoplasms | 2 | – | – |
 Renal carcinomas | 1 | – | – |