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Fig. 4 | Molecular Medicine

Fig. 4

From: hUCMSCs carrying exenatide prevent T1DM by improving intestinal microflora composition and islet tissue damage repair

Fig. 4

Bioinformatics analysis to screen the signaling pathways related to hUCMSCs@Ex-4 in the treatment of T1DM and changes in intestinal microflora. A Venn diagram of the exenatide-related genes and T1DM target genes determined using GeneCards. B The drug-target regulatory network. C GO enrichment analysis of 26 target genes. D, KEGG enrichment analysis of the 26 target genes. E Venn diagram of T1DM-related intestinal microflora predicted by the GMrepo, HMDAD, gutMEGA, and gutMDisorder databases. F Fecal intestinal microflora specie cladogram of T1DM mice treated with hUCMSCs@Ex-4 (red) and T1DM mice (green). G Differential fecal intestinal microflora species between T1DM mice treated with hUCMSCs@Ex-4 (red) and T1DM mice (green)

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Molecular Medicine

ISSN: 1528-3658