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Fig. 5 | Molecular Medicine

Fig. 5

From: hUCMSCs carrying exenatide prevent T1DM by improving intestinal microflora composition and islet tissue damage repair

Fig. 5

hUCMSCs@Ex-4 reduces the secretion pro-inflammatory cytokines while increasing that of anti-inflammatory cytokines in the serum of T1DM mice. A Serum levels of IL-1β in T1DM mice treated with hUCMSCs@Ex-4 measured by ELISA. B Serum levels of IL-6 in T1DM mice treated with hUCMSCs@Ex-4 measured by ELISA. C Serum levels of TNF-α in T1DM mice treated with hUCMSCs@Ex-4 measured by ELISA. D Serum levels of LPS in T1DM mice treated with hUCMSCs@Ex-4 measured by ELISA. E Serum levels of IL-10 in T1DM mice treated with hUCMSCs@Ex-4 measured by ELISA. F, Serum levels of IL-13 in T1DM mice treated with hUCMSCs@Ex-4 measured by ELISA. *p < 0.05 vs. T1DM mice. n = 12

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