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Fig. 6 | Molecular Medicine

Fig. 6

From: hUCMSCs carrying exenatide prevent T1DM by improving intestinal microflora composition and islet tissue damage repair

Fig. 6

Schematic representation of the regulatory network mechanisms of hUCMSCs@Ex-4 effects in T1DM. hUCMSCs@Ex-4 reduces the secretion of pro-inflammatory cytokines and modulates the abundances of pro-inflammatory intestinal bacteria, and promotes the secretion of anti-inflammatory cytokines, increasing the abundances of anti-inflammatory intestinal bacteria, thereby reducing blood glucose levels and promoting pancreatic islet tissue damage repair, ultimately alleviating of T1DM

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Molecular Medicine

ISSN: 1528-3658