Fig. 3

PNU treatment ameliorated DSS-induced colitis in mice. Mice received PNU-282987 treatment for 9 days. A Data for weight changes were recorded daily change from the starting body weight; B Disease activity index (DAI) was represented as average score of clinical symptoms including body weight changes, rectal bleeding and stool consistency or diarrhea; C and D Representative figure showing the colon length and spleen size for each group. The data are measured as the mean ± SD from 5 mice in each group; *P < 0.05, **P < 0.01, ***P < 0.001, compared with the IBD group