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Fig. 7 | Molecular Medicine

Fig. 7

From: Novel eIF4A1 inhibitors with anti‐tumor activity in lymphoma

Fig. 7

Docking poses of RBF197 and RBF208 in eIF4A:RNA groove. The top two panels show schematic representations of the interactions made between docked poses of RBF197 and RBF208 and their surrounding environments. Green, transparent ovals are used to two-dimensionally represent possible π-π stacking interactions between the ligands and surrounding residues. Dashed lines between the ligands and surrounding residues are used to indicate hydrogen bonding, where the color indicates the donor/acceptor character of the ligand atom (blue = donor; red = acceptor). The lower two panels are high-scoring docked models of RBF197 and RBF208

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