Fig. 1
From: Stem cell therapy as a promising strategy in necrotizing enterocolitis
Therapeutic effects of stem cells in NEC. Schematic illustrating the therapeutic effects of stem cells in the injured intestines of NEC model rats. With the injection of stem cells, the experimental NEC intestine has been shown to decrease inflammation, apoptosis, necrosis, and oxidant stress, balance bacteria, enhance barrier, inactivate TLR4, maintain ISC niche, improve motility, and promote IECs proliferation. ROS reactive oxygen species; LPS lipopolysaccharide; TLR4 toll-like receptor 4