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Fig. 6 | Molecular Medicine

Fig. 6

From: Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway

Fig. 6

p53 involves in S9-induced apoptosis but not cell cycle arrest. A U2OS cells and H1299 (p53 null) cells were treated with described concentration of S9 for 24 h. PARP and p53 protein levels were detected by western blot analysis. B, C U2OS p53+/+ and p53−/− cells were treated with described concentration of S9 for 24 h. PARP and p53 protein levels were detected by western blot analysis (B); stained with PI and analyzed by flow cytometry (C)

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Molecular Medicine

ISSN: 1528-3658