Fig. 1
From: Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis
Acid ceramidase (ASAH1) was increased in acute pancreatitis. A, B primary pancreatic acinar cells were treated with different concentrations of cerulein plus LPS (10Â ng/mL) for 6Â h (A) or treated with 200Â nM of cerulein plus LPS (10Â ng/mL) for indicated durations (B). C Mice injected with saline or cerulein plus LPS were sacrificed, and their pancreas samples were collected and lysed. Tissue lysate was examined by Western blotting with indicated antibodies (C)