Fig. 1
From: PACS-2 deficiency in tubular cells aggravates lipid-related kidney injury in diabetic kidney disease
Tubule-specific Pacs-2 deletion aggravates kidney injury in HFD/STZ treated mice. A and B Western blot and quantification of PACS-2 expression showing that PACS-2 was knocked out in renal cortex. C Body weight and D blood glucose are shown. E Kidney weight/body weight (KW/BW) ratio, F Urine albumin-to-creatinine ratio (UACR) and urinary NAG in mice are shown. G Morphological examinations of tubular and glomerular changes by HE, PAS, Masson staining. Scale bars: 50 μm. H and I Quantification of tubular damage score and glomerular damage score of the kidneys in each group. All data are presented as means ± SD; *p < 0.05, **p < 0.01, ***p < 0.001, ns, not significant. n = 6