Fig. 1

Ferroptosis is positively associated with neointima formation. A The presentative images and quantification of COX-2 mean fluorescence intensity (MFI) in mouse carotid artery after 4 weeks of ligation or not (n = 4 per group). Scale bar, 50 μm. B Perls’ Prussian blue staining of mouse carotid artery after 4 weeks of ligation. The correlation of intima/media and iron⁺ cells in neointimal formation (n = 11). r = 0.771, P = 0.0054. Scale bar, 100 μm. Data are presented as mean ± SEM, P values calculated by a two-tailed unpaired Student’s t-test. *P < 0.05