Fig. 2

Pyridostigmine administration reduces mortality in patients with severe COVID-19. (a) Cumulative incidence of mechanical ventilation or death by day 28 as the composite outcome; (b) cumulative incidence of mechanical ventilation day 28; (c) cumulative incidence of death by day 28;and,(d) cumulative incidence of discharge home by day 28. Hazard ratios were calculated with Cox proportional hazards models and p-values were obtained with a log-rank test. In the case of IMV as the primary outcome, deaths without IMV were censored. In the case of death as the primary outcome, IMV was not considered