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Fig. 3 | Molecular Medicine

Fig. 3

From: Chronotherapeutic neuroprotective effect of verapamil against lipopolysaccharide-induced neuroinflammation in mice through modulation of calcium-dependent genes

Fig. 3

Effect of VRP on histopathological examination by Bielschowsky silver staining and quantitative measurement of optical density of the silver staining. a Normal control, b LPS only, c Morning VRP, and d Evening VRP. Four different sectors were examined; 1: whole brain tissue, 2: CA1 area, 3: CA3 area, and 4: dentate gyrus area. Data are expressed as the mean ± SD and were analyzed using one-way ANOVA followed by Tukey post hoc test. Values were considered significantly different at P < 0.05. a: significant versus normal control, b: significant versus LPS only, and c: significant versus morning VRP. LPS: lipopolysaccharides, VRP: verapamil

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Molecular Medicine

ISSN: 1528-3658